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Ethical Consideration and the Advantage of Collaborative Study in TPRC.

Laboratory primates are thought to be the most important laboratory animal because of phylogenic close relation and similarity of various morphological as well as biological functions to human. However, the very unique facilities, equipments and management system must be established in consideration of their behavior, psychological and biological properties, since they are relatively large animals with higher intellectual ability.
   Tsukuba Primate Research Center has been preparing appropriate breeding, rearing and experimental facilities which can offer the psychological wellbeing and environment-enriched housing condition for laboratory primates. In addition, the skillful and experienced veterinarians and animal technicians can offer the well-trained technical supports that are effective on reduction of physical and psychological stress in laboratory primates under indoor environment. Both unique facilities and technical staffs in TPRC can guarantee the scientifically and ethically approved experiment using laboratory primates.

   The modern animal experiment requires the four "Rs", Replacement of animal experiment to other system without using animals, Reduction of number of animals used and experimental period, Refinement of experimental procedure to decrease the pain and agony of animals during experiment and Responsibility of researcher who conducts the animal experiment.
   The advantages of TPRC in modern animal experiment are as follow from view points of consideration to "Four Rs".
1) TPRC can offer the information about Replacement of animal experiment.
2) TPRC can provide the well-designed facility that is effective on the practice of Refined animal experiment.
3) The collaboration between researcher and well-trained technician can guarantee the Refinement and Reduction because the high level technical support make it possible to reduce the pain and the number of animals in experiment.
4) The collaborative study can guarantee the modern scientific animal experiment through the inspection of experimental procedure by each other between researcher and technician.